The run-up to the virtual session has already left a sour taste for the Palestinian leadership.
On Sunday, the Palestinian Authority (PA) accused the United Arab Emirates (UAE) and Bahrain of blocking a draft resolution that called on Arab states to adhere to the 2002 Arab Peace Initiative plan before normalising ties with Israel.
The Arab Initiative put forth by Saudi Arabia calls for establishing ties with Israel in exchange for its withdrawal to the 1967 borders, a just solution for Palestinian refugees, and occupied East Jerusalem as the capital of a future Palestinian state.
A senior member of the PA's governing Fatah faction, Hussein Hamayel, said Bahrain's opposition to the draft resolution "places it on the side of the enemies of the Arabs and Muslims".
However on Tuesday, in a bid to soften its tone, the official spokesman for PA President Mahmoud Abbas said the leader "will not accept insulting the national symbols of Arab nations, including the United Arab Emirates".
In a statement carried by the official news agency Wafa, Nabil Abu Rudeinah said the state of Palestine is keen on "maintaining brotherly relations with all Arab countries on the basis of mutual respect, with the necessity of the latter adhering to the Arab Peace Initiative".
'Betraying the cause'
Announced by US President Donald Trump on August 13, the UAE-Israeli normalisation agreement caught the PA by surprise, which then accused the UAE of betraying the Palestinian cause - long seen as a pan-Arab issue.
Israeli Prime Minister Benjamin Netanyahu said more Arab countries will soon follow in the UAE's steps, and Bahrain and Oman have both voiced support.
"The Palestinian cause has traditionally been a unifying theme for the Arab League, which this year appears to be more a cause for division, rendering the Arab League ever more irrelevant in managing the affairs of the Arab world," said Andreas Krieg, assistant professor of security studies at King's College London.
The motion to be put forth by the Palestinian leadership will likely not be endorsed by a number of Gulf states, he added.
"While there might not be an immediate move by any other Arab state to normalise ties with Israel formally, there will be more exchanges and engagement with Israel, which is no longer tied to the Palestinian cause," Kreig told Al Jazeera.
"For the UAE, Bahrain and Sudan, the Arab-Israeli conflict has been relegated to the Israeli-Palestinian problem, which should not be an obstacle to a warming of bilateral ties with Israel."
Marwa Fatafta, a policy member with the Palestinian policy network Al-Shabaka, agreed, saying geopolitical interests "trump the rights of Palestinians".
"Many Gulf states have keen interest in formalising ties with Israel and the UAE-Israel was the ice-breaker," she said. "Normalisation between Israel and Gulf states has already been in the making, and now it is just a matter of timing.
"What would probably come out from the Arab League is the usual recycled lip-service to the Palestinians," she added.